Start your journey at Myrtle Beach International Airport with Southwest Airlines.
Though it seems impossible to tire of sunshine, boardwalks, world-class golf courses, we all need to get away from home every once in a while. Ready for your next vacation? Explore everywhere you can book a flight to with Southwest. Hit the Great Lakes, the Capitol Region, the Rust Belt, and more. Whether you want to head up the Eastern Seaboard for the glitz and glamour of a big city or hop a connecting flight and travel to the other side of the country to see how things are done on the Pacific Coast, there are plenty of options when you book your flight with us. Grab your suitcase and start packing your bags for your next Southwest flight out of Myrtle Beach International Airport.
Myrtle Beach may be a magnet for tourists, but that doesn’t mean its denizens don’t want to explore the world beyond the beautiful Grand Strand. Start racking up Rapid Rewards points when you fly to wherever your wanderlust takes you away from the Atlantic Coast. Pack even more fun into your upcoming adventure with getaways from Southwest. What’re you waiting for? Book today and see for yourself what makes the Southwest® Experience exceptional.
Experience otherworldly theme parks or enjoy the down to earth vibes in this Central Florida city that’s the perfect steppingstone for once in a lifetime day trips.
Stroll tree lined streets in the sprawling City in a Forest, a hospitable Southern belle that’s home to cutting edge culinary stars, world class centers for the fine arts, and so much more.
The City of Bridges awaits! Whether you spend your time sightseeing all 446 bridges or want to learn more about the city’s Appalachian roots, Pittsburgh will not disappoint.
*Fares are updated hourly. Fares displayed on external channels may no longer be available at time of booking. To find the most updated fare, please visit Southwest.com. Restrictions and exclusions apply. Seats and dates are limited. Fares may vary by destination, flight, and day of week and won't be available on some flights that operate during very busy travel times and holiday periods.
Got flexible travel plans?
Use our Low Fare Calendar to find the lowest fares on flights from Myrtle Beach available inside your travel window.
Cities with daily nonstop flights Monday through Friday from MYR
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Cities with daily nonstop flights Saturday through Sunday from MYR
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*Fares are updated hourly. Fares displayed on external channels may no longer be available at time of booking. To find the most updated fare, please visit Southwest.com. Restrictions and exclusions apply. Seats and dates are limited. Fares may vary by destination, flight, and day of week and won't be available on some flights that operate during very busy travel times and holiday periods.
†Weekly flights based on DOT published scheduled average flights Monday through Sunday between 5/1/2025 and 5/31/2025. Note: route may not operate every day of the week.
‡Nonstop flights based on DOT published scheduled average flights Monday through Friday between 5/1/2025 and 5/31/2025.
§Nonstop flights based on DOT published scheduled average flights Saturday through Sunday between 5/1/2025 and 5/31/2025.
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